Here we have identified HIV-1 B clade Envelope (Env) amino acid signatures from early 4 Door Fridge in infection that may be favored at transmission, as well as patterns of recurrent mutation in chronic infection that may reflect common pathways of immune evasion.To accomplish this, we compared thousands of sequences derived by single genome amplif
The human brain is organized into a collection of interacting networks with specialized functions to support various cognitive functions.Recent research has reached a consensus that the brain manifests small-world topology, which implicates both global and local efficiency at minimal wiring costs, and also modular organization, which indicates func
Boid inclusion body disease (BIBD) is an often fatal disease affecting mainly constrictor snakes.BIBD has been associated with infection, and more recently with coinfection, by various reptarenavirus species (family Arenaviridae).Thus far BIBD has only been reported in captive snakes, and neither the incubation period nor the route of transmission
Background.Job burnout is an important factor affecting human health, and it can reduce the efficiency and effectiveness of staff in various organizations, including academic libraries.This negative phenomenon may deprive libraries of experienced manpower, disrupting the educational and information needs of library users, ultimately leading to the